It appears obvious that several of us are well-trained in the sciences and try to do a reasonable job of testing our perceptions of differences as to whether those exist or are suggestive effects (biases). The "cons" in High-End Audio are too often associated with grandiose, wide-sweeping claims of night and day difference (improvements).
I have also tried a few speaker cables. I do hear a difference, but in my opinion, and under non-controlled conditions, the differences were subtle. You might be interested in what I found in DBT/SBT in posts #6161, 6259, and 6640 under the topic of why DBT is such a hot button (started by JA).
There are changes that I can hear and repeat. There are others that I cannot hear. Of the latter, I found the green edge on CDs do not make it sound any different to me on my system. Yet I can repeatedly hear the difference between a fuse and a wire in line with the speaker cable.
Of the tweaks I have tried, most have improved the sound, such that I can hear more into the music and are able to enjoy it much more, compared to what I heard for many years before - without those tweaks. (To go into detail would be a very long post.)
One example is the substitution of film capacitors for electrolytics in the signal path. I tried this and it works in my equipment. I tried to see if there was any difference in square waves on a scope, before and after the tweak. I could not discern any difference at higher and lower signal levels. Yet the difference is plain to me, from my musical experience. The engineer part is still wondering what the change actually is.
Hope you can try some controlled tests and report what you find.
I am an occasional visitor to these forums, so don't hold your breath for a quick reply from me. Good luck and happy listening.